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The First Sanctum (Japanese: 第1聖具室, Dai-1 Seigushitsu) is a location in Xenoblade Chronicles. It is located off the elevated walkway around the Central Hall of Prison Island, and can only be accessed when Prison Island is revisited.

It is reached by proceeding from the Kitchen to the Pillar Control and dropping onto the Bone Pillar. If the Bone Pillar is in the raised position, the party must then jump off the north or south end of the pillar into a pool of water below; otherwise the party can walk along the pillar to these pools.

The Abnormal Clone Barg can be fought here.

Giants' Treasure Chests[]

First Sanctum DE Southeast Chest

Southeast Treasure Chest

There are two Giants' Treasure Chests in this room.

The southeast chest contains:

First Sanctum DE Southwest Chest

Southwest Treasure Chest

The southwest chest contains:

Gallery[]

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